内容

目次

SECTION I: GENERAL PRINCIPLES 1. Pharmacokinetics and Pharmacodynamics2. Drug Transport/Drug Transporters 3. Drug Metabolism 4. Pharmacogenomics 5.Principles of Therapeutics SECTION II: DRUGS ACTING AT SYNAPTIC ANDNEUROEFFECTOR JUNCTIONAL SITES 6. Neurotransmission: The Autonomic andSomatic Motor Nervous Systems 7. Muscarinic Receptor Agonists and Antagonists8. Anticholinesterase Agents 9. Agents Acting at the Neuromuscular Junctionand Autonomic Ganglia 10. Catecholamines, Sympathomimetic Drugs, andAdrenergic Receptor Antagonists 11. 5-Hydroxytryptamine (Serotonin) ReceptorAgonists and Antagonists SECTION III: DRUGS ACTING ON THE CENTRAL NERVOUSSYSTEM 12. Neurotransmission and the Central Nervous System 13. History andPrinciples of Anesthesiology; General Anesthetics 14. Local Anesthetics 15.The Therapeutic Gases: Oxygen, Carbon Dioxide, Nitric Oxide, and Helium 16.Hypnotics and Sedatives 17. Introduction to Psychopharmacology: DrugTherapy of Depression and Anxiety Disorders 18. Pharmacotherapy of Psychosisand Mania 19. Drugs Effective in the Therapy of the Epilepsies 20. Treatmentof Central Nervous System Degenerative Disorders 21. Opioid Analgesics 22.Ethanol 23. Drug Addiction and Drug Abuse SECTION IV: AUTACOIDS: DRUGTHERAPY OF INFLAMMATION Introduction 24. Histamine, Bradykinin, and TheirAntagonists 25. Lipid-Derived Autacoids: Eicosanoids and Platelet-ActivatingFactor 26. Analgesic-Antipyretic and Antiinflammatory Agents and DrugsEmployed in the Treatment of Gout 27. Drugs Used in the Treatment of AsthmaSECTION V: DRUGS AFFECTING RENAL AND CARDIOVASCULAR FUNCTION 28.Diuretics 29. Vasopressin and Other Agents Affecting the RenalConservation of Water 30. Renin and Angiotensin 31. Drugs Used for theTreatment of Myocardial Ischemia 32. Antihypertensive Agents and the DrugTherapy of Hypertension 33. Pharmacological Treatment of Heart Failure 34.Antiarrhythmic Drugs 35. Drug Therapy for Hypercholesterolemia andDyslipidemia SECTION VI: DRUGS AFFECTING GASTROINTESTINAL FUNCTION 36.Agents Used for Control of Gastric Acidity and Treatment of Peptic Ulcers andGastroesopheageal Reflux Disease 37. Prokinetic Agents, Antiemetics, andAgents Used in Irritable Bowel Syndrome 38. Agents Used of Diarrhea,Constipation, and Inflammatory Bowel Disease; Agents Used for Biliary andPancreatic Disease SECTION VII: CHEMOTHERAPY OF PARASITIC INFECTIONS 39.Drugs Used in the Chemotherapy of Protozoal Infections: Malaria 40. DrugsUsed in the Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis,Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other ProtozoalInfections 41. Drugs Used in the Chemotherapy of Helminthiasis SECTIONVIII: CHEMOTHERAPY OF MICROBIAL DISEASES 42. Antimicrobial Agents: GeneralConsiderations 43. Antimicrobial Agents (Continued): Sulfonamides,Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary TractInfections 44. Antimicrobial Agents: Penicillins, Cephalosporins, and Otherb-Lactam Antibiotics 45. Antimicrobial Agents: The Aminoglycosides 46.Antimicrobial Agents: Protein-Synthesis Inhibitors and MiscellaneousAntibacterial Agents 47. Antimicrobial Agents (Continued): Drugs Used in theChemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, andLeprosy 48. Antimicrobial Agents: Antifungal Agents 49. Antimicrobial Agents:Antiviral Agents (Nonretroviral) 50. Antimicrobial Agents: AntiretroviralAgents SECTION IX: CHEMOTHERAPY OF NEOPLASTIC DISEASES Introduction 51.Antineoplastic Agents SECTION X: DRUGS USED FOR IMMUNOMODULATION 52.Imunomodulators: Immunosuppressive Agents, Tolerogens, and ImmunostimulantsSECTION XI: DRUGS ACTING ON THE BLOOD AND THE BLOOD-FORMING ORGANS 53.Hematopoietic Agents: Growth Factors, Minerals, and Vitamins 54. BloodCoagulation and Anticoagulant, Thrombolytic, and Antiplatelet DrugsSECTION XII: HORMONES AND HORMONE ANTAGONISTS 55. Pituitary Hormones andTheir Hypothalamic Releasing Factors 56. Thyroid and Antithyroid Drugs 57.Estrogens and Progestins 58. Androgens 59. Adrenocorticotropic Hormone;Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of theSynthesis and Actions of Adrenocortical Hormones 60. Insulin, OralHypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas 61.Agents Affecting Calcification and Bone Turnover: Calcium, Phosphate,Parathyroid Hormone, Vitamin D, Calcitonin, and Other Compounds SECTIONXIII: DERMATOLOGY 62. Dermatological Pharmacology SECTION XIV:OPHTHALMOLOGY 63. Ocular Pharmacology SECTION XV: TOXICOLOGY 64. Principlesof Toxicology; Treatment of Poisoning 65. Poisoning; Heavy Metals andHeavy-Metal Antagonists APPENDICES I. Principles of Prescription OrderWriting and Patient Compliance II. Design and Optimization of DosageRegimens; Pharmacokinetic Data