内容

目次

Part 1 Evolution by natural selection: Darwin's theory; evolution "invitro"; Lamark, Weismann and the central dogma. Part 2 Models ofpopulations: models of population growth; selection in an asexualpopulation; the accuracy of replication; genetic drift in finitepopulations. Part 3 Evolution in diploid populations: gene frequenciesand the Hardy-Weinberg ratio; the concept of fitness; the spread of afavourable gene. Part 4 The variability of natural populations: theevidence for genetic variability; mutation; the maintenance ofvariation. Part 5 Evolution at more than one locus: linkagedisequilibrium; heterostyly in plants; mimicry in butterflies; linkagedisequilibrium in natural populations; normalizing selection andlinkage disequilibriums. Part 6 Quantitative genetics: nature andnurture; the additive genetic model; a more realistic model;experiments in artificial selection; quantitative variation andfitness; the maintenance of genetic variance for quantitative traits.Part 7 A model of phenotypic evolution: pairwise interactions; someextensions of the model; will a sexual population evolve to an ESS?Part 8 Finite and structured populations: inbreeding; genetic drift;the rate of neutral molecular evolution; mitochondrial DNA; migrationand differentiation between populations; the establishment of a newfavourable mutation. Part 9 Evolution in structured populations:selection in trait groups; the evolution of co-operation - synergisticselection, relatedness; the group as the unit of evolution; theshifting balance theory. Part 10 The evolution of prokaryotes: theevolution of gene function; phages, plasmids and transposable elements;the evolution of phages and their hosts, plasmids, transposons; thepopulation genetics of "E. coli"; the evolution of viruses. Part 11 Theevolution of the eukaryotic genome: the nature of the genome; thehaemoglobin gene family; duplication and the increase of DNA content;the ribosomal gene; unequal crossing over and gene conversion;repetitive DNA; karyotypic evolution. Part 12 The evolution of geneticsystems - sex and recombination: the natural history of eukaryotic sex;the evolutionary significance of sex; the evolution of recombination.Part 13 The evolution of genetic systems - some consequences of sex:the sex ratio; selfing and outcrossing; hermaphroditism; sexualselection. Part 14 Macroevolution: species and speciation; patterns ofevolution; coevolution.