内容

目次

I. GENERAL PRINCIPLES 1. What is pharmacology? 2. How drugs act: generalprinciples 3. How drugs act: molecular aspects 4. Cellular mechanisms:excitation, contraction, and secretion 5. Cellular mechanisms: cellproliferation and apoptosis 6. Method and measurement in pharmacology 7.Absorption and distribution of drugs 8. Drug elimination and pharmacokineticsII. CHEMICAL MEDIATORS 9. Chemical mediators and the autonomic nervoussystem 10. Cholinergic transmission 11. Noradrenergic transmission 12. Otherperipheral mediators 13. Peptides and proteins as mediators 14. Nitric oxide15. Local hormones, inflammation, and immune reactions 16. Anti-inflammatoryand immunosuppressant drugs III. DRUGS AFFECTING MAJOR ORGAN SYSTEMS 17. Theheart 18. The vascular system 19. Atherosclerosis and lipoprotein metabolism20. Haemostasis and thrombosis 21. The haemopoietic system 22. Therespiratory system 23. The kidney 24. The gastrointestinal tract 25. Theendocrine pancreas and the control of blood glucose 26. Obesity 27. Thepituitary and adrenal cortex 28. The thyroid 29. The reproductive system 30.Bone metabolism IV. THE NERVOUS SYSTEM 31. Chemical transmission and drugaction in the central nervous system 32. Amino acid transmitters 33. Othertransmitters and modulators 34. Neurodegenerative disorders 35. Generalanaesthetic agents 36. Anxiolytic and hypnotic drugs 37. Antipsychotic drugs38. Drugs used in affective disorders 39. Antiepileptic drugs 40. Analgesicdrugs 41. Central nervous system stimulants and psychotomimetic drugs 42.Drug dependence and drug abuse 43. Local anaesthetics V. DRUGS USED IN THETREATMENT OF INFECTIONS AND CANCER 44. Basic principles of chemotherapy 45.Antibacterial drugs 46. Antiviral drugs 47. Antifungal drugs 48.Antiprotozoal drugs 49. Antihelminthic drugs 50. Cancer chemotherapy VI.SPECIAL TOPICS 51. Individual variation and drug interaction 52. Harmfuleffects of drugs 53. Gene therapy 54. Drug discovery and developmentAppendix Index