内容

目次

Part I: Principles of Psychopharmacology. Neurotransmitters, receptors,signal transduction, and second messengers in psychiatric disorders. Basicprinciples of molecular biology and genomics. Chemical neuroanatomy of theprimate brain. Electrophysiology. Animal models. Psychoneuroendocrinology.Principles of pharmacokinetics and pharmacodynamics. Brain-immune systeminteractions: relevance to the pathophysiology and treatment ofneuropsychiatric disorders. Brain imaging in psychopharmacology. Statisticsand clinical trial design in psychopharmacology. Pharmacoeconomics. Part II:Classes of Psychiatric Treatments: animal and human pharmacology.Antidepressants and Anxiolytics. Tricyclic and tetracyclic drugs. Fluoxetine.Sertraline. Paroxetine. Fluvoxamine. Citalopram and s-citalopram. Monoamineoxidase inhibitors. Trazodone and nefazodone. Bupropion. Mirtazapine.Venlafaxine. Duloxetine and milnacipran. Benzodiazepines. Buspirone andgepirone. Investigational treatments for mood and anxiety disorders: CRHreceptor antagonists, NK-1 receptor antagonists, and glucocorticoid receptorantagonists. Antipsychotics. Classic antipsychotic medications. Clozapine.Olanzapine. Quetiapine. Aripiprazole. Risperidone. Ziprasidone. Drugs totreat extrapyramidal side effects. Drugs for Treatment of Bipolar Disorder.Lithium. Valproate. Carbamazepine and oxcarbazepine. Gabapentin. Lamotrigine.Topiramate. Other Agents. Cognitive enhancers. Sedative-hypnotics.Psychostimulants in psychiatry: amphetamine, methylphenidate, and modafinil.Electroconvulsive therapy. Part III: Clinical Psychobiology and PsychiatricSyndromes. Biology of mood disorders. Neurobiology of schizophrenia.Neurobiology of anxiety disorders. Biology of Alzheimer's disease.Neurobiology of substance abuse disorders. Biology of eating disorders.Biology of personality disorders. Part IV: Psychopharmacological Treatment.Treatment of depression. Treatment of bipolar disorder. Treatment ofschizophrenia. Treatment of anxiety disorders. Management of noncognitivesymptoms of dementia: behavioral and psychological symptoms of dementia.Treatment of childhood and adolescent disorders. Treatment ofsubstance-related disorders. Treatment of eating disorders. Treatment ofagitation and aggression in the elderly. Treatment of personality disorders.Psychiatric emergencies. Treatment during late life. Psychopharmacologyduring pregnancy and lactation. Treatment of insomnia. Index.