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丸善のおすすめ度
【非侵襲イメージングのドラックデリバリーへの応用－生体内分布から作用部位における妥当性確認】
Drug Delivery Applications of Noninvasive Imaging:Validation from Biodistribution to Sites of Action '13
Li, C
著
発行年月 |
2013年12月 |
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出版国 |
アメリカ合衆国 |
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言語 |
英語 |
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媒体 |
冊子 |
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装丁 |
hardcover |
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ページ数／巻数 |
478 p. |
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ジャンル |
洋書／生命科学・医学／基礎医学／薬理学 |
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ISBN |
9780470633472 |
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商品コード |
1007991125 |
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新刊案内掲載月 |
2012年02月 |
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商品URL
| https://kw.maruzen.co.jp/ims/itemDetail.html?itmCd=1007991125 |
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内容
Cost–effective strategies for designing novel drug deliverysystems that target a broad range of disease conditions In vivo imaging has become an important tool for thedevelopment of new drug delivery systems, shedding new light on thepharmacokinetics, biodistribution, bioavailability, localconcentration, and clearance of drug substances for the treatmentof human disease, most notably cancer. Written by a team ofinternational experts, this book examines the use of quantitativeimaging techniques in designing and evaluating novel drug deliverysystems and applications. Drug Delivery Applications of Noninvasive Imaging offersa full arsenal of tested and proven methods, practices andguidance, enabling readers to overcome the many challenges increating successful new drug delivery systems. The book begins withan introduction to molecular imaging. Next, it covers: In vivo imaging techniques and quantitativeanalysis Imaging drugs and drug carriers at the site of action,including low–molecular weight radiopharmaceuticals, peptides andproteins, siRNA, cells, and nanoparticles Applications of imaging techniques in administration routesother than intravenous injection, such as pulmonary and oraldelivery Translational research leading to clinical applications Imaging drug delivery in large animal models Clinical applications of imaging techniques to guide drugdevelopment and drug delivery Chapters are based on a thorough review of the currentliterature as well as the authors' firsthand experience workingwith imaging techniques for the development of novel drug deliverysystems. Presenting state–of–the–technology applications of imaging inpreclinical and clinical evaluation of drug delivery systems,Drug Delivery Applications of Noninvasive Imaging offerscost–effective strategies to pharmaceutical researchers andstudents for developing drug delivery systems that accuratelytarget a broad range of disease conditions.
