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SECTION 1: General aspects of vaccination 1 A short history of vaccination 1 2 Vaccine immunology 14 3 The vaccine industry 33 4 Vaccine manufacturing 44 5 Evolution of adjuvants across the centuries 58 6 Vaccine additives and manufacturing residuals in the United States: licensed vaccines 71 7 Passive immunization 80 8 General immunization practices 88 SECTION 2: Licensed vaccines 9 Adenovirus vaccines 113 10 Anthrax vaccines 127 11 Cholera vaccines 141 12 Diphtheria toxoid 153 13 Haemophilus influenzae vaccines 167 14 Hepatitis A vaccines 183 15 Hepatitis B vaccines 205 16 Human papillomavirus vaccines 235 17 Inactivated influenza vaccines 257 18 Influenza vaccine-live 294 19 Japanese encephalitis vaccines 312 20 Measles vaccines 352 21 Meningococcal vaccines 388 22 Mumps vaccine 419 23 Pertussis vaccines . 447 24 Plague vaccines 493 25 Pneumococcal conjugate vaccine and pneumococcal common protein vaccines 504 26 Pneumococcal polysaccharide vaccines 542 27 Poliovirus vaccine-inactivated . 573 28 Poliovirus vaccine-live 598 29 Rabies vaccines .646 30 Rotavirus vaccines . 669 31 Rubella vaccine 688 32 Smallpox and vaccinia 718 33 Tetanus toxoid 746 34 Tick-borne encephalitis virus vaccines 773 35 Tuberculosis vaccines 789 36 Typhoid fever vaccines 812 37 Varicella vaccine 837 38 Yellow fever vaccine 870 39 Zoster vaccine 969 40 Combination vaccines 981 SECTION 3: Vaccines in development and new vaccine strategies 41 Biodefense and special pathogen vaccines 1008 42 Therapeutic cancer vaccines 1018 43 Cytomegalovirus vaccines 1032 44 Dengue vaccines 1042 45 Diarrhea caused by bacteria 1052 46 Ebola vaccine 1060 47 Epstein-Barr virus vaccines 1068 48 Hepatitis C vaccines 1074 49 Hepatitis E vaccines 1085 50 Herpes simplex virus vaccines 1090 51 Human immunodeficiency virus vaccines 1097 52 Lyme disease vaccines 1122 53 Malaria vaccines 1133 54 Noninfectious disease vaccines 1138 55 Respiratory syncytial virus and parainfluenza virus vaccines 1146 56 Parasitic disease vaccines 1154 57 Staphylococcus aureus vaccines 1161 58 Streptococcus group A vaccines 1169 59 Streptococcus group B vaccines 1176 60 Technologies for making new vaccines 1182 61 Alternative vaccine delivery methods 1200 62 The development of gene-based vectors for immunization 1232 SECTION 4: Vaccination of special groups 63 Vaccination of immunocompromised hosts 1243 64 Vaccination of human immunodeficiency virus-infected persons 1257 65 Vaccines for international travel 1270 66 Vaccines for health care personnel 1290 SECTION 5: Public health and regulatory issues 67 Immunization in the United States 1310 68 Immunization in Europe . 1334 69 Immunization in the Asia-Pacific region 1353 70 Immunization in developing countries 1369 71 Community immunity 1395 72 Economic analyses of vaccine policies 1413 73 Regulation and testing of vaccines 1427 74 Regulation of vaccines in Europe 1447 75 Regulation of vaccines in developing countries 1454 76 Vaccine safety 1464 77 Legal issues . 1481 78 Ethics 1508