内容

目次

PART 1: THE BASICS OF DNA, CHROMOSOMES, CeLLS, AND DEVELOPMENT 1.Nucleic Acid Structure and Gene Expression 2. Chromosome Structure andFunction 3. Genes in Pedigrees and Populations 4. Cells and Cell-CellCommunication 5. Principles of Development PART 2: ANALYZING THE STRUCTUREAND EXPRESSION OF GENES AND GENOMES 6. Amplifying DNA: Cell-based DNA Cloningand PCR 7. Nucleic Acid Hybridization: Principles and Applications 8.Analyzing the Structure and Expression of Genes and Genomes PART 3:INVESTIGATING THE HUMAN GENOME AND ITS RELATIONSHIP TO OTHER GENOMES 9.Organization of the Human Genome 10. Model Organisms, Comparative Genomicsand Evolution 11. Human Gene Expression 12. Studying Gene Function in thePost-Genome Era PART 4: HUMAN GENETIC VARIATION AND DISEASES 13. HumanGenetic Variability and its Consequences 14. Genetic Mapping of MendelianCharacters 15. Mapping Genes Conferring Susceptibility to Complex Disease 16.Identifying Human Disease Genes and Susceptibility Factors 17. CancerGenetics PART 5: APPLIED HUMAN MOLECULAR GENETICS 18. Genetic Testing ofIndividuals 19. Pharmacogenetics, Personalized Medicine, and PopulationScreening 20. Genetic Manipulation of Animals for Modeling Disease andInvestigating Gene Function 21. Genetic Approaches to Treating Disease