Green Chemistry is a vitally important subject area in a world where being as green and environmentally sound as possible is no longer a luxury but a necessity. Its applications include the design of chemical products and processes that help to reduce or eliminate the use of generation of hazardous substances. The Handbook of Green Chemistry comprises 12 volumes, split into subject–specific sets as follows: Set I:        Green Catalysis Set II:      Green Solvents Set III:     Green Processes Volume 7: Green Synthesis Volume 8: Green Nanoscience Volume 9: Designing Safer Chemicals Set IV:     Green Products Classical organic synthesis involves the use of non–renewable feedstock, batch reactors and refluxing, all of which are viewed negatively in a world where the drive for reusability and sustainability is the main focus. The aim of this book is to address the issues associated with organic synthesis and show how the area can be made more “green” and to provide new ideas for further innovations in the field of greener syntheses. The topics cover a wide range from starting materials, reaction design, choice of solvent, energy input, to reactor design.