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SECTION 1 INTRODUCTION1 An approach to the interpretation of skin biopsies2 Diagnostic cluesSECTION 2 TISSUE REACTION PATTERNS3 The lichenoid reaction pattern (　\interface dermatitis　　)4 The psoriasiform reaction pattern5 The spongiotic reaction pattern6 The vesiculobullous reaction pattern7 The granulomatous reaction pattern8 The vasculopathic reaction patternSECTION 3 THE EPIDERMIS9 Disorders of epidermal maturation and keratinization10 Disorders of pigmentationSECTION 4 THE DERMIS11 Disorders of collagen12 Disorders of elastic tissue13 Cutaneous mucinoses14 Cutaneous deposits15 Diseases of cutaneous appendages16 Cysts, sinuses and pits17 PanniculitisSECTION 5 THE SKIN IN SYSTEMIC AND MISCELLANEOUS 　DISEASES18 Metabolic and storage diseases19 Miscellaneous conditions20 Cutaneous drug reactions21 Reactions to physical agentsSECTION 6 INFECTIONS AND INFESTATIONS22 Cutaneous infections and infestations -- histological patterns23 Bacterial and rickettsial infections24 Spirochetal infections25 Mycoses and algal infections26 Viral diseases27 Protozoal infections28 Marine injuries29 Helminth infestations30 Arthropod-induced diseasesSECTION 7 TUMORS31 Tumors of the epidermis32 Lentigines, nevi and melanomas33 Tumors of cutaneous appendages34 Tumors and tumor-like proliferations of fibrous and related tissues35 Tumors of fat36 Tumors of muscle, cartilage and bone37 Neural and neuroendocrine tumors38 Vascular tumors39 Cutaneous metastases40 Cutaneous infiltrates -- non-lymphoid41 Cutaneous infiltrates -- lymphoid and leukemic