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VOLUME 1 DIAGNOSTIC STRATEGIES AND GENERAL TOPICS 1. Introduction to the 11th Edition of the Manual of Clinical Microbiology 2. Microscopy 3. Laboratory Detection of Bacteremia and Fungemia 4. Systems for Identification of Bacteria and Fungi 5. Automation and Design of the Clinical Microbiology Laboratory 6. Molecular Microbiology 7. Immunoassays for Diagnosis of Infectious Diseases 8. Prevention of Health Care-Associated Infections 9. Investigation of Disease Outbreaks 10. Molecular Epidemiology 11. Procedures for the Storage of Microorganisms 12. Prevention of Laboratory-Acquired Infections 13. Decontamination, Disinfection, and Sterilization 14. Biothreat Agents 15. The Human Microbiome 16. Microbial Genomics and Pathogen Discovery BACTERIOLOGY 17. Taxonomy and Classification of Bacteria 18. Specimen Collection, Transport, and Processing: Bacteriology 19. Reagents, Stains, and Media: Bacteriology Gram-Positive Cocci 20. General Approaches to Identification of Aerobic Gram-Positive Cocci 21. Staphylococcus, Micrococcus, and Other Catalase-Positive Cocci 22. Streptococcus 23. Enterococcus 24. Aerococcus, Abiotrophia, and Other Aerobic Catalase-Negative, Gram-Positive Cocci Gram-Positive Rods 25. General Approaches to the Identification of Aerobic Gram-Positive Rods 26. Bacillus and Other Aerobic Endospore-Forming Bacteria 27. Listeria and Erysipelothrix 28. Coryneform Gram-Positive Rods 29. Nocardia, Rhodococcus, Gordonia, Actinomadura, Streptomyces, and Other Aerobic Actinomycetes 30. Mycobacterium: General Characteristics, Laboratory Detection, and Staining Procedures 31. Mycobacterium: Laboratory Characteristics of Slowly Growing Mycobacteria 32. Mycobacterium: Clinical and Laboratory Characteristics of Rapidly Growing Mycobacteria Gram-Negative Bacteria 33. Approaches to the Identification of AerobicGram-Negative Bacteria 34. Neisseria 35. Aggregatibacter, Capnocytophaga, Eikenella, Kingella, Pasteurella, and Other Fastidious or Rarely Encountered Gram-Negative Rods 36. Haemophilus 37. Escherichia, Shigella, and Salmonella 38. Klebsiella, Enterobacter, Citrobacter, Cronobacter, Serratia, Plesiomonas, and Other Enterobacteriaceae 39. Yersinia 40. Aeromonas 41. Vibrio and Related Organisms 42. Pseudomonas 43. Burkholderia, Stenotrophomonas, Ralstonia, Cupriavidus, Pandoraea, Brevundimonas, Comamonas, Delftia, and Acidovorax 44. Acinetobacter, Chryseobacterium, Moraxella, and Other Nonfermentative Gram-Negative Rods 45. Bordetella and Related Genera 46. Francisella 47. Brucella 48. Bartonella 49. Legionella Anaerobic Bacteria 50. Approaches to Identification of Anaerobic Bacteria 51. Peptostreptococcus, Finegoldia, Anaerococcus, Peptoniphilus, Veillonella, and Other Anaerobic Cocci 52. Propionibacterium, Lactobacillus, Actinomyces, and Other Non-Spore-Forming Anaerobic Gram-Positive Rods 53. Clostridium 54. Bacteroides , Porphyromonas , Prevotella , Fusobacterium , and Other Anaerobic Gram-Negative Rods Curved and Spiral-Shaped Gram-Negative Rods 55. Algorithms for Identification of Curved and Spiral-Shaped Gram-Negative Rods 56. Campylobacter and Arcobacter 57. Helicobacter 58. Leptospira 59. Borrelia 60. Treponema and Brachyspira , Human Host-Associated Spirochetes Mycoplasmas and Obligate Intracellular Bacteria 61. General Approaches to Identification of Mycoplasma, Ureaplasma, and Obligate Intracellular Bacteria 62. Mycoplasma and Ureaplasma 63. Chlamydiaceae 64. Rickettsia and Orientia 65. Ehrlichia, Anaplasma, and Related Intracellular Bacteria 66. Coxiella 67. Tropheryma whipplei ANTIBACTERIAL AGENTS AND SUSCEPTIBILITY TEST METHODS 68. Antibacterial Agents 69. Mechanisms of Resistance to Antibacterial Agents 70. Susceptibility Test Methods: General Considerations 71. Susceptibility Test Methods: Dilution and Disk Diffusion Methods 72. Antimicrobial Susceptibility Testing Systems 73. Special Phenotypic Methods for Detecting Antibacterial Resistance 74. Susceptibility Test Methods: Fastidious Bacteria 75. Susceptibility Test Methods: Anaerobic Bacteria 76. Susceptibility Test Methods: Mycobacteria, Nocardia, and Other Actinomycetes 77. Molecular Detection of Antibacterial Drug Resistance VOLUME 2 VIROLOGY General 78. Taxonomy and Classification of Viruses 79. Specimen Collection, Transport, and Processing: Virology 80. Reagents, Stains, Media, and Cell Cultures: Virology 81. Algorithms for Detection and Identification of Viruses RNA Viruses 82. Human Immunodeficiency Viruses 83. Human T-Cell Lymphotropic Viruses 84. Influenza Viruses 85. Parainfluenza and Mumps Viruses 86. Respiratory Syncytial Virus and Human Metapneumovirus 87. Measles and Rubella Viruses 88. Enteroviruses and Parechoviruses 89. Rhinoviruses 90. Coronaviruses 91. Hepatitis A and E Viruses 92. Hepatitis C Virus 93. Gastroenteritis Viruses 94. Rabies Virus 95. Arboviruses 96. Hantaviruses 97. Arenaviruses and Filoviruses DNA Viruses 98. Herpes Simplex Viruses and Herpes B Virus 99. Varicella-Zoster Virus 100. Human Cytomegalovirus 101. Epstein-Barr Virus 102. Human Herpesviruses 6, 7, and 8 103. Adenoviruses 104. Human Papillomaviruses 105. Human Polyomaviruses 106. Parvovirus B19 and Bocaviruses 107. Poxviruses 108. Hepatitis B and D Viruses Subviral Agents 109. Transmissible Spongiform Encephalopathies ANTIVIRAL AGENTS AND SUSCEPTIBILITY TEST METHODS 110. Antiviral Agents 111. Mechanisms of Resistance to Antiviral Agents 112. Susceptibility Test Methods: Viruses MYCOLOGY 113. Taxonomy and Classification of Fungi 114. Specimen Collection, Transport, and Processing: Mycology 115. Reagents, Stains, and Media: Mycology 116. General Approaches for Direct Detection and Identification of Fungi Fungi 117. Candida, Cryptococcus, and Other Yeasts of Medical Importance 118. Pneumocystis 119. Aspergillus and Penicillium 120. Fusarium and Other Opportunistic Hyaline Fungi 121. Agents of Systemic and Subcutaneous Mucormycosis and Entomophthoromycosis 122. Histoplasma, Blastomyces, Coccidioides, and Other Dimorphic Fungi Causing Systemic Mycoses 123. Trichophyton, Microsporum, Epidermophyton, and Agents of Superficial Mycoses 124. Curvularia, Exophiala, Scedosporium, Sporothrix, and Other Melanized Fungi 125. Fungi Causing Eumycotic Mycetoma 126. Mycotoxins 127. Lacazia, Lagenidium, Pythium, and Rhinosporidium 128. Microsporidia ANTIFUNGAL AGENTS AND SUSCEPTIBILITY TEST METHODS 129. Antifungal Agents 130. Mechanisms of Resistance to Antifungal Agents 131. Susceptibility Test Methods: Yeasts and Filamentous Fungi PARASITOLOGY General 132. Taxonomy and Classification of Human Parasitic Protozoa and Helminths 133. Specimen Collection, Transport, and Processing: Parasitology 134. Reagents, Stains, and Media: Parasitology 135. General Approaches for Detection and Identification of Parasites Parasites 136. Plasmodium and Babesia 137. Leishmania and Trypanosoma 138. Toxoplasma 139. Pathogenic and Opportunistic Free-Living Amebae 140. Intestinal and Urogenital Amebae, Flagellates, and Ciliates 141. Cystoisospora, Cyclospora, and Sarcocystis 142. Cryptosporidium 143. Nematodes 144. Filarial Nematodes 145. Cestodes 146. Trematodes 147. Less Common Helminths 148. Arthropods of Medical Importance ANTIPARASITIC AGENTS AND SUSCEPTIBILITY TEST METHODS 149. Antiparasitic Agents 150. Mechanisms of Resistance to Antiparasitic Agents 151. Susceptibility Test Methods: Parasites