内容

目次

Part I. General Principles 1. Historical Background and Overview 2. Monosaccharides and Their Linkages 3. Oligosaccharides and Polysaccharides 4. Cellular Organization of Glycosylation 5. Glycosylation Precursors 6. Glycosyltransferases and Glycan-processing Enzymes 7. Biological Functions of Glycans 8. A Genomic View of Glycobiology Part II. Structure and Biosynthesis 9. N-Glycans 10. O-GalNAc Glycans 11. Glycosphingolipids 12. Glycosylphosphatidylinositol Anchors 13. Other Classes of Eukaryotic Glycans 14. Structures Common to Different Glycans 15. Sialic Acids and other Nonulosonic Acids 16. Hyaluronan 17. Proteoglycans and Sulfated Glycosaminoglycans 18. Nucleocytoplasmic Glycosylation 19. The O-GlcNAc Modification Part III. Glycans in Evolution and Development 20. Evolution of Glycan Diversity 21. Eubacteria 22. Archaea 23. Fungi 24. Viridiplantae and Algae 25. Nematoda 26. Arthropoda 27. Deuterostomes Part IV. Glycan-binding Proteins 28. Discovery and Classification of Glycan-Binding Proteins 29. Principles of Glycan Recognition 30. Structural Biology of Glycan Recognition 31. R-type Lectins 32. L-type Lectins 33. P-type Lectins 34. C-type Lectins 35. I-type Lectins 36. Galectins 37. Microbial Lectins: Hemagglutinins, Adhesins, and Toxins 38. Proteins that Bind Sulfated Glycosaminoglycans Part V. Glycans in Physiology and Disease 39. Glycans in Glycoprotein Quality Control 40. Free Glycans as Signaling Molecules 41. Glycans in Systemic Physiology 42. Bacterial and Viral Infections 43. Parasitic Infections 44. Genetic Disorders of Glycan Degradation 45. Genetic Disorders of Glycosylation 46. Glycans in Acquired Human Diseases 47. Glycosylation Changes in Cancer Part VI. Methods and Applications 48. Antibodies and Lectins in Glycan Analysis 49. Glycosylation Mutants of Cultured Cells 50. Structural Analysis of Glycans 51. Glycomics and Glycoproteomics 52. Glycobioinformatics 53. Chemical Synthesis of Glycans and Glycoconjugates 54. Enzymatic Synthesis of Glycans and Glycoconjugates 55. Chemical Tools for Inhibiting Glycosylation 56. Glycosylation Engineering 57. Glycans in Biotechnology and Pharmaceutical Industry 58. Glycans in Nanotechnology 59. Glycans in Bioenergy and Material Science Part VII. Future Directions 60. Future Directions in the Glycosciences