New and Future Developments in Microbial Biotechnology and Bioengineering
目次
Section A. Chemistry and biosynthesis 1. Peptide and peptide-derivative antibiotics 2. Polyketide derivatives 3. Other groups of bioactive products Section B. Genetics and bioengineering 1. Preparation of high production microorganisms 2. Genetic manipulation of secondary metabolites producers 3. Bioengineering of secondary metabolites 4. Secondary metabolites: from metabolic engineering to synthetic biology/Metabolomics for secondary metabolites Section C. Obtaining new bioactive secondary metabolites 1. Isolation from natural resources 2. Producers of bioactive compounds 3. Semi-synthetic and synthetic bioactive products 4. Hybrid bioactive products and combinatorion biosynthesis Section D. Regulation of secondary metabolites production 1. Growth phases of microbial culture 2. Control of fermentation by basal nutrients 3. How signals from the medium are received 4. Regulation by low molecular compounds 5. Autoregulators 6. Regulation by metal ions Section E. Resistance to secondary metabolites 1. Resistance of bioactive secondary metabolites producers 2. Resistance in pathogenic microorganisms
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