内容

目次

Part 1. Introduction to the CRISPR Revolution.- 1. Viral Vectors, Engineered Cells and the CRISPR Revolution.- 2.  Combining Engineered Nucleases with Adeno-associated Viral Vectors for Therapeutic Gene Editing.- Part 2. CRISPR in Model Systems.-  3. From Reductionism to Holism: Toward a More Complete View of Development through Genome Engineering.- 4. Genome Engineering in Mice.- 5. Genome Editing to Study Ca2+ Homeostasis in Zebrafish Cone Photoreceptors.- 6. From Prokaryotic Immune Systems to Plant Genome Editing Tools.- 7. Part 3. The Future of CRISPR.- 7. Using High-throughput Gene Editing to Identify Therapeutic Targets in the Noncoding Genome.- 8. CRISPR in the Retina: Evaluation of Future Potential.- 9. The Future of CRISPR Applications in the Lab, the Clinic and Society.