目次

PART I INTRODUCTION1. Organoids and mini-organs: Introduction, history, and potential PART II CONSTRUCTING ORGANOIDS2. Elements of organoid design3. Intestinal organoids: Mini-guts grown in the laboratory4. Three-dimensional breast culture models5. Prostate organoids: Directed differentiation from embryonic stem cells6. Kidney organoids7. Spontaneous self-assembly of liver organoids from differentiated human cells8. Cerebral organoids: Building brains from stem cells9. From organoids to mini-organs: A case study in the kidney PART III APPLICATIONS OF ORGANOIDS10. Intestinal organoids: A model for biomedical and nutritional research11. A three-dimensional neurosphere system using human stem cells for nanotoxicology studies12. Organoids for modeling kidney disease13. Intestinal organoids in studying host2bacterial interactions14. Four challenges for organoid engineers