目次

Part I: Clinical Metabolomics and Lipidomics 1. Metabolomics as a Tool to Understand Pathophysiological Processes             Julijana Ivanisevic and Aurelien Thomas 2. Metabolomics in Immunology Research             Bart Everts Part II: LC-MS-Based Metabolomics 3. LC-MS-Based Metabolomics of Biofluids Using All Ion Fragmentation (AIF) Acquisition             Romanas Chaleckis, Shama Naz, Isabel Meisterll, and Craig E. Wheelock 4. Lipid Mediator Metabolomics via LC-MS/MS Profiling and Analysis             Jesmond Dalli, Romain A. Colas, Mary E. Walker, and Charles N. Serhan 5. UHPSFC/ESI-MS Analysis of Lipids             Miroslav Lísa and Michal Holčapek 6. LC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples             Yiu Yiu Lee and Jetty Chung-Yung Lee 7. Serum Testosterone by Liquid Chromatography Tandem Mass Spectrometry for Routine Clinical Diagnostics             Lennart J. van Winden, Olaf van Tellingen, Huub H. van Rossum 8. LC-MS/MS Analysis of Bile Acids             Sabrina Krautbauer and Gerhard Liebisch 9. LC-MS/MS Analysis of Triglycerides in Blood-Derived Samples             Madlen Sander, Susen Becker, and Uta Ceglarek 10. LC-MS/MS Analysis of the Epoxides and Diols Derived from the Endocannabinoid Arachidonoyl Ethanolamide             Amy A. Rand, Patrick O. Helmer, Bora Inceoglu, Bruce D. Hammock, and Christophe Morisseau 11. Sphingolipid Analysis in Clinical Research             Bo Burla, Sneha Muralidharan, Markus R. Wenk, and Federico Torta 12. Shotgun Lipidomics Approach for Clinical Samples             Lars F. Eggers and Dominik Schwudke 13. Establishing and Performing Targeted Multi-Residue Analysis for Lipid Mediators and Fatty Acids in Small Clinical Plasma Samples             Theresa L. Pedersen and John W. Newman 14. Chemical Isotope Labeling LC-MS for Human Blood Metabolome Analysis             Wei Han and Liang Li 15. Direct Infusion-Tandem Mass Spectrometry (DI-MS/MS) Analysis of Complex Lipids in Human Plasma & Serum Using the LipidyzerTM Platform             Baljit K. Ubhi Part III: GC-MS-Based Metabolomics 16. Exploratory GC-MS-Based Metabolomics of Body Fluids             Carole Migné, Stéphanie Durand, and Estelle Pujos-Guillot 17. GC-MS Analysis of Short-Chain Fatty Acids in Feces, Cecum Content, and Blood-Derived Samples             Lisa Hoving, Marieke Heijink, Vanessa van Harmelen, Ko Willems van Dijk, and Martin Giera 18. GC-MS Analysis of Medium- and Long-Chain Fatty Acids in Blood Samples             Lisa Hoving, Marieke Heijink, Vanessa van Harmelen, Ko Willems van Dijk, and Martin Giera 19. Analysis of Oxysterols             Fabien Riols and Justine Bertrand-Michel 20. Analysis of Metabolites from the Tricarboxylic Acid Cycle for Yeast and Bacteria Samples Using Gas Chromatography Mass Spectrometry             Reza Maleki Seifar, Angela ten Pierick, and Patricia T.N. van Dam 21. GC-MS Analysis of Lipid Oxidation Products in Blood, Urine, and Tissue Samples             Anne Barden and Trevor A. Mori Part IV: CE-MS-Based Metabolomics 22. Metabolic Profiling of Urine by Capillary Electrophoresis-Mass Spectrometry Using Non-Covalently Coated Capillaries             Rawi Ramautar 23. CE-MS for the Analysis of Amino Acids             Karina Trevisan Rodrigues, Marina Franco Maggi Tavares, and Ann Van Schepdael Part V: NMR-Based Metabolomics 24. NMR Analysis of Fecal Samples             Hye Kyong Kim, Sarantos Kostidis, and Young Hae Choi 25. Quantitative Analysis of Central Energy Metabolism in Cell Culture Samples             Sarantos Kostidis Part VI: MALDI-Based Techniques and Mass Spectrometry Imaging of Clinical Samples 26. Mass Spectrometry Imaging of Metabolites             Benjamin Balluff and Liam A. McDonnell Part VII: Study Design, Data Analysis, and Bioinformatics 27. Quality Assured Biobanking: The Leiden University Medical Center Model             Rianne Haumann and Hein W. Verspaget 28. Extracting Knowledge from MS Clinical Metabolomic Data: Processing and Analysis Strategies             Julien Boccard and Serge Rudaz