目次

PART A. GENERAL PRINCIPLES 1. Anatomy, physiology and pharmacology of the Autonomic nervous system 2. Classification of Autonomic disorders a. autonomic failure b. autonomic hyperactivity c. orthostatic intolerance 3. General evaluation of autonomic disorders a. History and examination b. Syndrome specific evaluation 4. Principles of managements of autonomic disorders a. Orthostatic hypotension b. Gastrointestinal and genitourinary manifestations c. Autonomic hyperactivity PART B. CLINICAL CASES Scenario 1. Acute or subacute Pure autonomic failure Case 1.1. Autoimmune Autonomic ganglionopathy. Differential diagnosis: paraneoneoplastic disorders  Scenario 2. Chronic and progressive Pure autonomic failure Case 2.1. Pure Autonomic Failure (PAF) Scenario 3. Chronic autonomic failure associated with Parkinsonism, ataxia or dementia Case 3.1. Parkinson’s disease (PD). Differential diagnosis: Lewy body Dementia Case 3.2. Multiple System Atrophy (MSA). Differential diagnosis: MSA sub type Parkinsonism versus PD Scenario 4. Autonomic failure in chronic peripheral neuropathy Case 4.1. Diabetes Mellitus - Diabetic autonomic dysfunction in different organs  Case 4.2. Amyloidosis - Amyloidotic autonomic neuropathies Scenario 5. Autonomic failure in subacute sensory ganglioneuronopathies Case 5.1. Sjögren’s Syndrome. Differential diagnosis: paraneoplastic disorders Scenario 6. Autonomic failure and acute motor weakness Case 6.1. GBS. Differential Diagnosis: Botulism, Porphyria, Lambert Eaton Syndrome Scenario 7. Distal painful autonomic neuropathy Case 7.1. Small fiber neuropathy. Differential diagnosis: HIV, Fabry Disease, Alcohol  Scenario 8. Orthostatic intolerance Case 8.1. Vasovagal Syncope. Differential diagnosis: other reflex syncope, cardiac syncope, carotid sinus  Case 8.2. Postural Orthostatic Tachycardia Syndrome (POTS) Scenario 9. Autonomic hyperactivity Case 9.1. Severe brain injury