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SECTION I: HSP70 in Neuro-OnCOlogical Disorders Chapter 1. Heat Shock Protein 70 and Molecular Confession during NeurodegenerationKomal Panchal, Ajay Kumar and Anand K. TiwariGenetics & Developmental Biology LaboratoryIndian Institute of Advanced Research/IARGandhinagar, India  Chapter 2. Hsp70-Family Proteins and Neurodegenerative DiseasesZheying Sun, Roy J. Blackburn, Laura J. Blair and John Koren IIIDepartment of Molecular MedicineUniversity of South FloridaTampa, FL Chapter 3. Heat Shock Protein70 in Neurological Disease  Pinar Ortan, Ozden Yildirim Akan and Ferda HosgorlerDivision of NeurologySB University Izmir Bozyaka Training and Research HospitalAlsancak Izmir, Turkey Chapter 4. Involvement of Heat Shock Protein 70 (Hsp70) in Gastrointestinal CancersDipamoy Datta, Suparna Banerjee, Anupama Ghosh, Soumyajit Banerjee Mustafi, Prosenjit Sen and Sanghamitra RahaDepartment of BiotechnologyVisva-BharatiSantiniketan, India Chapter 5. Heat Shock Protein 70 and CancerTuoen Liu and Shousong CaoDepartment of Biomedical SciencesWest Virginia School of Osteopathic MedicineLewisburg, USA  Chapter 6. Implication of HSP70 in the Pathogenesis of Gastric CancerPrakash Chand Sharma and Renu VermaUniversity School of BiotechnologyGuru Gobind Singh Indraprastha UniversityNew Delhi, India SECTION II: HSP70 IN Circulatory Disorders Chapter 7. Double Face of eHsp70 in Front of Different SituationsMaria M. Barreca and Fabiana GeraciDepartment of Biological, Chemical and Pharmaceutical Sciences and TechnologiesUniversity of Palermo and Euro-Mediterranean Institute of Science and TechnologyPalermo, Italy Chapter 8. HSP70 is a Major Contributor to the MHCII Ligandome and Inducer of Regulatory T CellsWillem van Eden, Femke Broere and Ruurd van der ZeeDivision of ImmunologyUtrecht UniversityUtrecht, The Netherlands Chapter 9. Immune Properties of HSP70Yves Delneste, Vincent Larochette and Pascale JeanninUniversité d’Angers and LabEx ImmunoGraftOnco and Laboratory of Immunology and Allergology, University Hospital of AngersAngers, France Chapter 10. Molecular Chaperones Regulating the Dynamics, Composition and Functionality of RNP Granules: Implications for Age-related DiseasesDaniel Mateju, Laura Mediani, Federica F. Morelli, Simon Alberti and Serena Carra Department of Biomedical, Metabolic and Neural SciencesUniversity of Modena and Reggio EmiliaModena, Italy Chapter 11. Heat Shock Proteins in Cardiovascular Diseases: From Bench to BedsideFrancesca Bonomini, Gaia Favero, Valentina Trapletti and Rita RezzaniDepartment of Clinical and Experimental SciencesUniversity of BresciaUniversity of Brescia, Italy Chapter 12. Clinical Implication of Heat Shock Protein 70 in Kidney DiseaseAlev Yilmaz and Zeynep Nagehan Yuruk YildirimIstanbul University Istanbul Faculty of MedicinePediatric Nephrology DepartmentIstanbul, Turkey Chapter 13. Heat Shock Proteins in the Kidney - What is Known About their Role in Kidney Disease Shobhana Nayak RaoDepartment of NephrologyK.S. Hegde Medical Academy Medical Sciences ComplexDerlakatte, India Chapter 14. Heat Shock Protein 70 and Other Heat Shock Proteins in Diseased Retina Ting Zhang, Bobak Bahrami and Ling ZhuSave Sight InstituteThe University of SydneySydney, Australia SECTION III: HSP70 as a Therapeutic target Chapter 15. Emerging Role of HSP70 in Human DiseasesAnjali Garg, Bandana Kumari and Manish KumarDepartment of BiophysicsUniversity of Delhi South CampusNew Delhi, India Chapter 16. Intranasal Administration of Hsp70: Molecular and Therapeutic Consequences  Evgen’ev Michail, Garbuz David, Morozov Alexey and Bobkova NataliaEngelhardt Institute of Molecular BiologyInstitute of Cell BiophysicsPushchino, Russia  Chapter 17. The Effectiveness of Antitumor Vaccine Enriched with a Heat Shock Protein 70Gennadiy Didenko, Olena Kruts, Larysa Skivka and Yuriy PrylutskyyTaras Shevchenko National University of KyivKyiv, Ukraine Chapter 18. Mammalian Heat Shock Protein Hsp105: The Hsp70 Inducer and a Potent Target for Cancer TherapyYouhei Saito and Yuji NakayamaDepartment of Biochemistry and Molecular BiologyKyoto Pharmaceutical UniversityKyoto, Japan Chapter 19. Suppression of HSP70 Expression by Quercetin and its Therapeutic Potential against CancerEvren Önay Uçar, Aslıhan Şengelen, Elif Mertoğlu, Murat Pekmez and Nazlı ArdaDepartment of Molecular Biology & Genetics, Faculty of Science, Istanbul University, Istanbul, Turkey. Chapter 20. Hsp70 in Fungi: Evolution, Function and Vaccine CandidateShraddha Tiwari and Jata ShankarDepartment of Biotechnology and BioinformaticsJaypee University of Information Technology Solan, India