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PART I: QUESTIONS: INTRODUCING DEVELOPMENTAL BIOLOGY 1. Comprehending Development 2. Developmental Genetics 3. Cell-Cell Communication in Development PART II: SPECIFICATION: INTRODUCING CELL COMMITMENT AND EARLY EMBRYONIC DEVELOPMENT 4. Fertilization 5. Early Development in Invertebrates: Rapid Specification in Snails and Nematodes 6. The Genetics of Axis Specification in Drosophila 7. The Deuterostome Invertebrates: Sea Urchins and Tunicates 8. Early Development in Vertebrates: Amphibians and Fish 9. Early Development in Vertebrates: Birds and Mammals PART III: THE STEM CELL CONCEPT: INTRODUCING ORGANOGENESIS 10. The Emergence of the Ectoderm 11. Neural Crest Cells and Axonal Specificity 12. Paraxial and Intermediate Mesoderm 13. Lateral Plate Mesoderm and Endoderm 14. Development of the Tetrapod Limb 15. Sex Determination 16. Metamorphosis, Regeneration, and Aging 17. The Saga of the Germ Line PART IV: SYSTEMS BIOLOGY: EXPANDING DEVELOPMENTAL BIOLOGY TO MEDICINE, ECOLOGY, AND EVOLUTION 18. Medical Aspects of Developmental Biology 19. Developmental Plasticity and Symbiosis 20. Developmental Mechanisms of Evolutionary Change