内容

目次

1. Introduction2. Hereditary TRP Channelopathies3. Changes in TRP Channel Expression in Acquired Diseases4. TRP Gene Polymorphism and Disease Risk5. Topical Capsaicin for Pain Relief6. TRPV1 agonist cytotoxicity for chronic pain relief7. Intravesical Capsaicin and Resiniferatoxin for Bladder Disorders8. Clinical and Preclinical Experience with TRPV1 Antagonists as Potential Analgesic Agents 9. TRPA1 Antagonists for Pain Relief10. TRPA Antagonistsas Therapeutic Strategies to Reduce the Symptoms and Pathophysiology of Respiratory Disorders11. TRPV3 Receptors as Drug Targets: A Decade of Learning12. Small Molecule Agonists and Antagonists of TRPV413. Potential Therapeutic Applications for TRPV4 Antagonists in Lung Disease14. TRPM8 as a Target for Analgesia15. TRP Channels: Connectivity to Cerebral Vascular Disease16. TRP Channels' Key Role in the Transduction of Itch17. Role of TRP Channels in Skin Diseases18. TRP Channels in Obesity/Metabolic Syndrome19. TRP Channels in Diabetes20. TRP Channels and Ca²+ Entry in Cardiac Disease21. The Contribution of TRP Channels to Pathophysiological Regulation of the Gastrointestinal Tract22. Cancer: Oncogenic and Anti-Oncogenic TRP Channels as Biomarkers and Therapeutic Targets23. TRP Channels in the Brain24. A: Mucolipidosis and TRPML Channels24 B: TRPML1-dependent Processes as the Therapeutic Targets25. TRPs in respiratory disorders: opportunities beyond TRPA126. Concluding Remarks