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SECTION 1: BIOLOGICAL BASIS OF CHILDHOOD CANCER 1 Epidemiology of Childhood Cancer 2 Childhood Cancer and Heredity 3 Molecular and Genetic Basis of Childhood Cancer 4 Biology of Childhood Cancer 5 Tumor Immunology and Pediatric Cancer SECTION 2: DIAGNOSIS AND EVALUATION OF THE CHILD WITH CANCER 6 Clinical Assessment and Differential Diagnosis of the Child with Suspected Cancer 7 Pathology and Molecular Diagnosis of Leukemias and Lymphomas 8 Diagnostic Pathology of Pediatric Malignancies 9 Imaging Studies in the Diagnosis and Management of Pediatric Malignancies SECTION 3: PRINCIPLES OF MULTIMODAL THERAPY 10 General Principles of Chemotherapy 11 Molecularly Targeted Therapies and Biotherapeutics 12 General Principles of Surgery 13 General Principles of Radiation Oncology 14 Adoptive Cellular Immunotherapy 15 Adolescents and Young Adults with Cancer 16 Hematopoietic Stem Cell Transplantation in Pediatric Oncology 17 Cancer Clinical Trials: Design, Conduct, Analysis, and Reporting 18 Maximizing Safety in Cancer Treatment SECTION 4: MANAGEMENT OF COMMON CANCERS OF CHILDHOOD 19 Acute Lymphoblastic Leukemia 20 Acute Myeloid Leukemia and Myelodysplastic Syndromes 21 Myeloproliferative Neoplasms of Childhood 22 Hodgkin Lymphoma 23 Malignant Non-Hodgkin Lymphomas in Children 24 Lymphoproliferative Disorders and Malignancies Related to Immunodeficiencies 25 Histiocytic Diseases 26A Gliomas, Ependymomas, and Other Nonembryonal Tumors of the Central Nervous System 26B Embryonal and Pineal Region Tumors 27 Retinoblastoma 28 Liver Tumors 29 Renal Tumors 30 Neuroblastoma 31 Rhabdomyosarcoma 32 The Nonrhabdomyosarcoma Soft Tissue Sarcoma 33 Ewing Sarcoma 34 Osteosarcoma 35 Germ Cell Tumors 36 Endocrine Tumors 37 Rare Pediatric Tumors SECTION 5: SUPPORTIVE CARE OF CHILDREN WITH CANCER 38 Oncologic Emergencies 39 Hematologic Supportive Care for Children with Cancer 40 Infectious Complications in Pediatric Cancer Patients 41 Nutritional Supportive Care 42 Pain and Symptom Management 43 Nursing Support of the Child with Cancer 44 Rehabilitation of the Child with?Cancer 45 Psychiatric and Psychosocial Support for the Child and Family 46 The Other Side of the Bed: What Caregivers Can Learn from Listening to Patients and Their Families 47 Ethical Considerations in Pediatric Oncology SECTION 6: OTHER ISSUES ARISING AT DIAGNOSIS, DURING TREATMENT, AND AFTER CESSATION OF THERAPY 48 Late Effects of Childhood Cancer and its Treatment 49 Educational Issues for Children with Cancer 50 Palliative Care for the Child with Cancer 51 Economic Issues in Pediatric Cancer 52 Pediatric Cancer Policy and Case Advocacy on Insurance, Education, and Employment 53 Complementary and Alternative Medical Therapies in Pediatric Oncology 54 Pediatric Oncology in Countries with Limited Resources Index