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【高島明彦(学習院大学)他編・タウの生物学】

Tau Biology (Advances in Experimental Medicine and Biology, Vol. 1184) '20

Takashima, Akihiko, Wolozin, Benjamin, Buee, Luc  編
在庫状況 海外在庫有り  お届け予定日 1ヶ月  数量 冊 
価格 特価  \33,501(税込)         

発行年月 2020年02月
出版社/提供元
出版国 シンガポール
言語 英語
媒体 冊子
装丁 hardcover
ページ数/巻数 XI, 416 p. 83 illus., 75 illus. in color.
ジャンル 洋書/生命科学・医学/神経・精神科学/神経科学
ISBN 9789813293571
商品コード 1030622478
本の性格 学術書
新刊案内掲載月 2020年02月
商品URL
参照
https://kw.maruzen.co.jp/ims/itemDetail.html?itmCd=1030622478

内容

This book presents essential studies and cutting-edge research results on tau, which is attracting increasing interest as a target for the treatment of Alzheimer's disease. Tau is well known as a microtubule-associated protein that is predominantly localized in the axons of neurons. In various forms of brain disease, neuronal loss occurs, with deposition of hyperphosphorylated tau in the remaining neurons. Important questions remain regarding the way in which tau forms hyperphosphorylated and fibrillar deposits in neurons, and whether tau aggregation represents the toxic pathway leading to neuronal death. With the help of new technologies, researchers are now solving these long-standing questions. In this book, readers will find the latest expert knowledge on all aspects of tau biology, including the structure and role of the tau molecule, tau localization and function, the pathology, drivers, and markers of tauopathies, tau aggregation, and treatments targeting tau. Tau Biology will be an invaluable source of information and fresh ideas for those involved in the development of more effective therapies and for all who seek a better understanding of the biology of the aging brain.

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