著者紹介

内容

目次

Introduction to Protein-Protein Interactions: Protein-Protein ComplexDetermination by X-ray Crystallography and Interface Analysis of KnownStructures (J Janin); Protein-Protein Complex Determination and Analysis ofInteractions Using NMR Spectroscopy (J Werner); Perspective onProtein-Protein Interactions in Macromolecular Assemblies (R Bahadur);Energetics of Protein-Protein Interactions (I Jelezarov); Kinetics of ComplexFormation: Theory and Experiment (R Wade); Prediction of Putative ProteinInteraction Regions and Interaction Geometries: Prediction of ProteinInteraction Regions Based on Evolutionary Information (O Lichtarge);Prediction of Interaction Regions and Scoring Optimization (M Zacharias);Protein-Protein Docking Methods: A General Overview (C Prevost); Refinementof Docking Solutions (C Camacho); High-Resolution Docking IncludingConformational Flexibility (O Furman); Experimental Constraint-Driven Docking(A Bonvin); Design and Targeting of Protein-Protein Interactions by Drugs andProtein Mimetics: Protein-Protein Interaction Modules of Medical Importance(H Sticht); Prediction/Calculation of Protein-Protein Binding Affinities andMutation Effects (Fiorucci et al.); Design of Protein Mimetics That Interferewith Protein-Protein Interactions (K Mayo); Identifying Molecules to InhibitProtein-Protein Interactions (T Berg); Combining Bioinformatics andExperiment to Design Inhibitors of Protein-Protein Interactions (G Colombo).