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GENOME SEQUENCE ANALYSISAnnotation of genomes From sequence to consequence: in silico hypothesis generation and testing The atlas visualisation of genome-wide informationCONSTRUCTION OF DNA MICROARRAYSMicroarray design for bacterial genomesGlass slides microarrays for bacterial genomesCOMPARAIVE NUCLEIC ACID ANALYSIS Representational display analysis of Cdna and genome comparisonsApplication of DNA microarrays for comparative and evolutionary genomicsGene expression during host-pathogen interactions: approaches to bacterial mRNA extraction and labelling for microarray analysisHigh throughput in vivo screens: signature-tagged mutagenesisFurther strategies for signature-tagged mutagenesis and the application of oligonucleotide microarrays for the quantitation of DNA-tagged strainsPROTEOME ANALYSISAdvances in bacterial proteome analysisDiscovery of protein-protein interaction using two-hybrid systemsSECTION V APPLICATIONS OF MICROBIAL GENOMICS Cloning the metagenome: Culture-independent access to the diversity and functions of the uncultivated microbial worldReverse vaccinology: from genome to vaccineMicrobial genomics for antibiotic target discovery CASE STUDIES - BACTERIAHelicobacter pylori functional genomics Streptomyces coelicolor A3(2): from genome sequence to functionFunctional analysis of the Bacillus subtilis genomeSECTION VII CASE STUDIES - PARASITESPlasmodium falciparum DNA microarrays and interpretation of dataFunctional analysis of the Plasmodium falciparum genome using transfectionChromosome fragmentation as an approach to whole genome analysis in trypanosomes