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目次

THE ORIGINS OF RNA AND RNA AT THE ORIGIN 1. Setting the Stage. TheHistory, Chemistry, and Geobiology behind RNA 2. Progress towardUnderstanding the Origin of the RNA World 3. Protocells: Genetic PolymersInside Membrane Vesicles BUILDING A FUNCTIONAL RNA 4. Riboswitches andthe RNA World 5. Catalytic Strategies of Self-cleaving Ribozymes: Relicsof an RNA World? 6. How the Group I Intron Works: A Case Study of RNAStructure and Function EXITING THE ANCIENT RNA WORLD - SYNTHETASES ANDRIBOSOMES 7. RNA, Lipids, and Membranes 8. Aminoacyl tRNA Synthetases:From the RNA World to the Theater of Proteins 9. The Roles of RNA in theSynthesis of Protein 10. Evolution of Ribosomes and Translation from anRNA World RICHNESS OF RNA ROLES IN MODERN RNA WORLD 11. The RNA World12. The Ever-Growing World of Small Nuclear Ribonucleoproteins 13.Spliceosome Structure and Function 14. Urdine Insertion/Deletion RNAEditing as a Paradigm for Site-specific Modifications of RNA Molecules 15.Telomerase RNA 16. The Shapely mRNA: Knotting Ventured, Knotting GainedRNA CONTINUES TO TRIUMPH OVER DNA 17. Group II Introns: Ribozymes thatSplice RNA and Invade DNA 18. SINEs and LINEs: Troublemakers, Saboteurs,Benefactors, Ancestors 19. The Biology of Short RNAs 20. VersatileRoles of Small RNA Regulators in Bacteria 21. Large Noncoding RNAs inMammalian Gene Dosage Regulation EMERGING TOOLS 22. Predicting RNASecondary Structure 23. A Modular and Hierarchical Approach for All-AtomRNA Modeling 24. Automated In Vitro Selection and Microarray Applicationsfor Functional RNA Sequences 25. RNA Folding, Unfolding, and Dynamics, OneMolecule at a Time Appendix Index