Biotechnology Second, Completely Revised Edition Edited by H.–J. Rehm and G. Reed in cooperation with A. Pühler and P. Stadler This fully revised and expanded Second Edition takes into account all recent developments in biotechnology. It is extraordinarily broad in scope, up–to–date, carefully structured and well–balanced. "Biotechnology" considers both basic concepts and widely–differing industrial applications: it is a successful synthesis of theory and practice. Any scientist aiming for success in industrial microbiology, biochemistry, molecular biology and chemical engineering must turn to "Biotechnology". Volume 4: This volume covers monitoring of the biotechnological process with sophisticated analytical techniques, use of the resulting data by means of mathematical models, and computer–aided control for improvement of the productivity of biotechnological processes. Topics included are: ?? Methods and Instruments ?? Biosensors ?? Characterization of Bioreactors ?? Determination of Cell Concentration ?? Cell Models ?? Stirred Tank Models ?? Tower Reactor Models ?? Process Models ?? Control of Bioreactor Systems ?? Automation ?? Control of Downstream Processing