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Multiscale Mechanobiology in Tissue Engineering (Frontiers of Biomechanics, Vol. 3) '18

Lacroix, Damien, Brunelli, Marzia, Perrault, Cécile, Baldit, Adrien, Shariatzadeh, Maryam, Campos Marin, Ana, Castro, Andre, Barreto, Sara 　著

在庫状況海外在庫有り	お届け予定日 1ヶ月
価格 \23,871（税込）

発行年月	2018年08月
出版社／提供元	Springer International Publishing
出版国	シンガポール
言語	英語
媒体	冊子
装丁	hardcover
ページ数／巻数	xiii, 203 p., 2 illus. 1 in color
ジャンル	洋書／理工学／総合・複合工学／医用生体工学
ISBN	9789811080746
商品コード	1026627398
本の性格	学術書
新刊案内掲載月	2018年06月
商品URL	https://kw.maruzen.co.jp/ims/itemDetail.html?itmCd=1026627398

内容

This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.

A review of bioreactors and mechanical stimuli.- Multiscale simulation of bioreactor design and in vitro conditions.- Mechanical stimulation in a PCL additive manufacturing scaffold.- Towards a new approach to analyse quality control and morphometric variability in a scaffold.- Computational simulation of cell seeding in a tissue engineering scaffold.- Collagen gel cell encapsulation to study mechanotransduction.- Collagen gel cell encapsulation to study the effect of fluid flow on mechanotransduction.- Computational modeling of collagen hydrogel.- Mechanical load transfer at the cellular level.- Quantification of CSK mechanics and deformation in relation to cellular functioning.- The future of tissue engineering design for bioreactor stimulation.